In Vitro Characterization of Scaffolds for Tissue Engineering - A Review

Aarti Baliga, Shashikant Borkar

Biodegradability, Cytotoxicity, Porosity, Proliferation, Scaffolds.

Scaffolds are artificial structures that replace the natural extracellular matrix (ECM). Scaffolds are capable of supporting three dimensional tissue formations. The natural ECM performs functions, like regulating intercellular communication along with providing support to the cells. A variety of fabricating methods are adopted for preparing scaffolds from a wide range of available biomaterials. The scaffolds thus produced can function as a successful scaffold only if they satisfy the necessary parameters. The suitability of any scaffold for tissue engineering application is tested by using a battery of tests that is a combination of mechanical and biological tests. This paper reviews the test methods adopted by researchers to test the suitability of scaffolds for tissue engineering applications.

10.22161/ijaers/3.10.33